Application
Dansyl chloride has been used:
• as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)[4]
• in the derivatization of plasma samples[5][6]
• in the quantification of immobilized alkaline phosphatase[7]
一种用于氨基酸和肽的荧光N-末端衍生化的荧光试剂,并且可用反相HPLC进行检测。
1, 5, 25 g in glass bottle
Biochem/physiol Actions
Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins.[1] Dansyl chloride is used for derivatization of free amino acids and amines[2] in neural samples and biological fluids.[3] It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.[3]
Related Categories | Amino Acid Analysis, Detection Products for Amino Acid Analysis, Peptide Analysis and Characterization,Peptides, 生化试剂 Less... |
product line | BioReagent |
assay | ≥99% (HPLC) |
form | powder and chunks |
color | yellow to yellow-orange |
mp | 72-74 °C (lit.) |
solubility | acetone: 20 mg/mL |
suitability | suitable for amino acid labeling |
storage temp. | −20°C |
SMILES string | CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O |
InChI | 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3 |
InChI key | XPDXVDYUQZHFPV-UHFFFAOYSA-N |
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